The current research projects of the Maternal-Fetal Immunobiology Unit include the following:
1. The role of the NLRP3 inflammasome in preterm labor and birth
2. The role of T cells and macrophages at the maternal-fetal interface in patients with preterm labor and birth.
3. Immunotherapy approaches to treat and prevent preterm labor and birth
4. The biology of immune cells in the amniotic cavity and placenta
5. Host-microbe interactions in pregnancy
6. Discovery of immunobiomarkers of pregnancy complications.
Our closed collaborators include (http://prb.med.wayne.edu/research-divisions/center-for-advanced-obstetrical-care-research/):
1. Professor Roberto Romero. Branch Chief, Perinatology Research Branch
2. Professor Chaur-Dong Hsu. Chair, Department of Obstetrics and Gynecology
3. Professor Adi L. Tarca. Section Head Bioinformatics and Computational Biology Unit of the Perinatology Research Branch
4. Assistant Professor Kevin Theis. Sectional Head of the Maternal-Fetal Microbiome Unit of the Perinatology Research Branch
5. Associate Professor Roger Pique-Regi. Section head of the Maternal-Fetal Single-Cell Genomics Unit of the Perinatology Research Branch