Wayne State University

Warrior strong
Login
Search

School of Medicine

Gomez-Lopez Lab

Publications

View full list of publications through Pubmed.

Selected Published Peer-Review Journals

  1. Garcia-Flores V, Romero R, Peyvandipour A, Galaz J, Pusod E, Panaitescu B, Miller D, Xu Y, Tao L, Liu Z, Tarca AL, Pique-Regi R, Gomez-Lopez N. A single-cell atlas of murine reproductive tissues during preterm labor. Cell Rep. 2023 Jan 31;42(1):111846. doi: 10.1016/j.celrep.2022.111846. 
  2. Garcia-Flores V, Xu Y, Pusod E, Romero R, Pique-Regi R, Gomez-Lopez N. Preparation of single-cell suspensions from the human placenta. Nat Protoc. 2022 Nov 30. doi: 10.1038/s41596-022-00772-w.
  3. Miller D, Garcia-Flores V, Romero R, Galaz J, Pique-Regi R, Gomez-Lopez N. Single-Cell Immunobiology of the Maternal-Fetal Interface. J Immunol. 2022 Oct 15;209(8):1450-1464. doi: 10.4049/jimmunol.2200433.
  4. Motomura K, Romero R, Galaz J, Tao L, Garcia-Flores V, Xu Y, Done B, Arenas-Hernandez M, Miller D, Gutierrez-Contreras P, Farias-Jofre M, Aras S, Grossman LI, Tarca AL, Gomez-Lopez N. Fetal and maternal NLRP3 signaling is required for preterm labor and birth. JCI Insight. 2022 Aug 22;7(16):e158238. doi: 10.1172/jci.insight.158238. PMID: 35993366; PMCID: PMC9462488
  5. Demery-Poulos C, Romero R, Xu Y, Arenas-Hernandez M, Miller D, Tao L, Galaz J, Farias-Jofre M, Bhatti G, Garcia-Flores V, Seyerle M, Tarca AL, Gomez-Lopez N. Pregnancy imparts distinct systemic adaptive immune function. Am J Reprod Immunol. 2022 Aug 21:e13606. doi: 10.1111/aji.13606. Epub ahead of print. PMID: 35989229
  6. Greenberg JM, Romero R, Winters AD, Galaz J, Garcia-Flores V, Arenas-Hernandez M, Panzer J, Shaffer Z, Kracht DJ, Gomez-Lopez N, Theis KR. Microbiota of the Pregnant Mouse: Characterization of the Bacterial Communities in the Oral Cavity, Lung, Intestine, and Vagina through Culture and DNA Sequencing. Microbiol Spectr. 2022 Aug 31;10(4):e0128622. doi: 10.1128/spectrum.01286-22. Epub 2022 Aug 2. PMID: 35916526; PMCID: PMC9430855
  7. Miller D, Romero R, Kacerovsky M, Musilova I, Galaz J, Garcia-Flores V, Xu Y, Pusod E, Demery-Poulos C, Gutierrez-Contreras P, Liu TN, Jung E, Theis KR, Coleman LA, Gomez-Lopez N. Defining a role for Interferon Epsilon in normal and complicated pregnancies. Heliyon. 2022 Jul 16;8(7):e09952. doi: 10.1016/j.heliyon.2022.e09952. PMID: 35898609; PMCID: PMC9309660
  8. Gudicha DW, Romero R, Gomez-Lopez N, Galaz J, Bhatti G, Done B, Jung E, Gallo DM, Bosco M, Suksai M, Diaz-Primera R, Chaemsaithong P, Gotsch F, Berry SM, Chaiworapongsa T, Tarca AL. The amniotic fluid proteome predicts imminent preterm delivery in asymptomatic women with a short cervix. Sci Rep. 2022 Jul 11;12(1):11781. doi: 10.1038/s41598-022-15392-3. PMID: 35821507; PMCID: PMC9276779
  9. Galaz J, Romero R, Arenas-Hernandez M, Farias-Jofre M, Motomura K, Liu Z, Kawahara N, Demery-Poulos C, Liu TN, Padron J, Panaitescu B, Gomez-Lopez N. Clarithromycin prevents preterm birth and neonatal mortality by dampening alarmin-induced maternal-fetal inflammation in mice. BMC Pregnancy Childbirth. 2022 Jun 20;22(1):503. doi: 10.1186/s12884-022-04764-2. PMID: 35725425; PMCID: PMC9210693
  10. Gallo DM, Romero R, Bosco M, Chaiworapongsa T, Gomez-Lopez N, Arenas-Hernandez M, Jung E, Suksai M, Gotsch F, Erez O, Tarca AL. Maternal plasma cytokines and the subsequent risk of uterine atony and postpartum hemorrhage. J Perinat Med. 2022 Jun 21. doi: 10.1515/jpm-2022-0211. Epub ahead of print. PMID: 35724639
  11. Gomez-Lopez N, Galaz J, Miller D, Farias-Jofre M, Liu Z, Arenas-Hernandez M, Garcia-Flores V, Shaffer Z, Greenberg JM, Theis KR, Romero R. The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal-fetal homeostasis. Reproduction. 2022 Jun 20;164(2):R11-R45. doi: 10.1530/REP-22-0046. PMID: 35559791; PMCID: PMC9233101
  12. Farias-Jofre M, Romero R, Galaz J, Xu Y, Tao L, Demery-Poulos C, Arenas-Hernandez M, Bhatti G, Liu Z, Kawahara N, Kanninen T, Shaffer Z, Chaiworapongsa T, Theis KR, Tarca AL, Gomez-Lopez N. Pregnancy tailors endotoxin-induced monocyte and neutrophil responses in the maternal circulation. Inflamm Res. 2022 Jun;71(5-6):653-668. doi: 10.1007/s00011-022-01569-z. Epub 2022 Apr 21. PMID: 35445873; PMCID: PMC9021564
  13. Gomez-Lopez N, Romero R, Tao L, Gershater M, Leng Y, Zou C, Farias-Jofre M, Galaz J, Miller D, Tarca AL, Arenas-Hernandez M, Bhatti G, Garcia-Flores V, Liu Z, Para R, Kanninen T, Hadaya O, Paredes C, Xu Y. Distinct Cellular Immune Responses to SARS-CoV-2 in Pregnant Women. J Immunol. 2022 Apr 15;208(8):1857-1872. doi: 10.4049/jimmunol.2101123. Epub 2022 Apr 4. PMID: 35379748
  14. Gershater M, Romero R, Arenas-Hernandez M, Galaz J, Motomura K, Tao L, Xu Y, Miller D, Pique-Regi R, Martinez G 3rd, Liu Y, Jung E, Para R, Gomez-Lopez N. IL-22 Plays a Dual Role in the Amniotic Cavity: Tissue Injury and Host Defense against Microbes in Preterm Labor. J Immunol. 2022 Apr 1;208(7):1595-1615. doi: 10.4049/jimmunol.2100439. Epub 2022 Mar 18. PMID: 35304419; PMCID: PMC8976826
  15. Pique-Regi R, Romero R, Garcia-Flores V, Peyvandipour A, Tarca AL, Pusod E, Galaz J, Miller D, Bhatti G, Para R, Kanninen T, Hadaya O, Paredes C, Motomura K, Johnson JR, Jung E, Hsu CD, Berry SM, Gomez-Lopez N. A single-cell atlas of the myometrium in human parturition. JCI Insight. 2022 Mar 8;7(5):e153921. doi: 10.1172/jci.insight.153921. PMID: 35260533; PMCID: PMC8983148
  16. Garcia-Flores V, Romero R, Xu Y, Theis KR, Arenas-Hernandez M, Miller D, Peyvandipour A, Bhatti G, Galaz J, Gershater M, Levenson D, Pusod E, Tao L, Kracht D, Florova V, Leng Y, Motomura K, Para R, Faucett M, Hsu CD, Zhang G, Tarca AL, Pique-Regi R, Gomez-Lopez N. Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2. Nat Commun. 2022 Jan 18;13(1):320. doi: 10.1038/s41467-021-27745-z. PMID: 35042863; PMCID: PMC8766450
  17. Gomez-Lopez N, Garcia-Flores V, Chin PY, Groome HM, Bijland MT, Diener KR, Romero R, Robertson SA. Macrophages exert homeostatic actions in pregnancy to protect against preterm birth and fetal inflammatory injury. JCI Insight. 2021 Oct 8;6(19):e146089. doi: 10.1172/jci.insight.146089. PMID: 34622802
  18. Tarca AL, Pataki BÁ, Romero R, Sirota M, Guan Y, Kutum R, Gomez-Lopez N, Done B, Bhatti G, Yu T, Andreoletti G, Chaiworapongsa T; DREAM Preterm Birth Prediction Challenge Consortium, Hassan SS, Hsu CD, Aghaeepour N, Stolovitzky G, Csabai I, Costello JC. Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth. Cell Rep Med. 2021 Jun 15;2(6):100323. doi: 10.1016/j.xcrm.2021.100323. PMID: 34195686
  19. Motomura K, Romero R, Galaz J, Tarca AL, Done B, Xu Y, Leng Y, Garcia-Flores V, Arenas-Hernandez M, Theis KR, Gershater M, Jung E, Hsu CD, Gomez-Lopez N. RNA Sequencing Reveals Distinct Immune Responses in the Chorioamniotic Membranes of Women with Preterm Labor and Microbial or Sterile Intra-Amniotic Inflammation. Infect Immun. 2021 Apr 16;89(5):e00819-20. doi: 10.1128/IAI.00819-20. PMID: 33558326
  20. Miller D, Motomura K, Galaz J, Gershater M, Lee ED, Romero R, Gomez-Lopez N. Cellular immune responses in the pathophysiology of preeclampsia. J Leukoc Biol. 2021 Apr 13. doi: 10.1002/JLB.5RU1120-787RR. PMID: 33847419
  21. Gomez-Lopez N, Romero R, Varrey A, Leng Y, Miller D, Done B, Xu Y, Bhatti G, Motomura K, Gershater M, Pique-Regi R, Tarca AL. RNA Sequencing Reveals Diverse Functions of Amniotic Fluid Neutrophils and Monocytes/Macrophages in Intra-Amniotic Infection. J Innate Immun. 2021;13(2):63-82. doi: 10.1159/000509718. PMID: 33152737
  22. Pique-Regi R, Romero R, Tarca AL, Luca F, Xu Y, Alazizi A, Leng Y, Hsu CD, Gomez-Lopez N. Does the human placenta express the canonical cell entry mediators for SARS-CoV-2? Elife. 2020 Jul 14;9:e58716. doi: 10.7554/eLife.58716. PMID: 32662421 
  23. Gomez-Lopez N, Arenas-Hernandez M, Romero R, Miller D, Garcia-Flores V, Leng Y, Xu Y, Galaz J, Hassan SS, Hsu CD, Tse H, Sanchez-Torres C, Done B, Tarca AL. Regulatory T Cells Play a Role in a Subset of Idiopathic Preterm Labor/Birth and Adverse Neonatal Outcomes. Cell Rep. 2020 Jul 7;32(1):107874. doi: 10.1016/j.celrep.2020.107874. PMID: 32640239
  24. Motomura K, Romero R, Xu Y, Theis KR, Galaz J, Winters AD, Slutsky R, Garcia-Flores V, Zou C, Levenson D, Para R, Ahmad MM, Miller D, Hsu CD, Gomez-Lopez N. Intra-Amniotic Infection With Ureaplasma parvum Causes Preterm Birth and Neonatal Mortality That Are Prevented by Treatment With Clarithromycin. mBio. 2020 Jun 23;11(3):e00797-20. doi: 10.1128/mBio.00797-20. PMID: 32576673
  25. Miller D, Gershater M, Slutsky R, Romero R, Gomez-Lopez N. Maternal and Fetal T Cells in Term Pregnancy and Preterm Labor. Cell Mol Immunol. 2020 Jul;17(7):693-704. doi: 10.1038/s41423-020-0471-2. Epub 2020 May 28. PMID: 32467619
  26. Theis KR, Romero R, Winters AD, Jobe AH, Gomez-Lopez N. Lack of Evidence for Microbiota in the Placental and Fetal Tissues of Rhesus Macaques. mSphere. 2020 May 6;5(3):e00210-20. doi: 10.1128/mSphere.00210-20. PMID: 32376701
  27. Garcia-Flores V, Romero R, Furcron AE, Levenson D, Galaz J, Zou C, Hassan SS, Hsu CD, Olson D, Metz GAS, Gomez-Lopez N. Prenatal Maternal Stress Causes Preterm Birth and Affects Neonatal Adaptive Immunity in Mice. Front Immunol. 2020 Feb 26;11:254. doi: 10.3389/fimmu.2020.00254. eCollection 2020. PMID: 32174914
  28. Theis KR, Romero R, Greenberg JM, Winters AD, Garcia-Flores V, Motomura K, Ahmad MM, Galaz J, Arenas-Hernandez M, Gomez-Lopez N. No Consistent Evidence for Microbiota in Murine Placental and Fetal Tissues. mSphere. 2020 Feb 26;5(1):e00933-19. doi: 10.1128/mSphere.00933-19. PMID: 32102944
  29. Tarca AL, Romero R, Pique-Regi R, Pacora P, Done B, Kacerovsky M, Bhatti G, Jaiman S, Hassan SS, Hsu CD, Gomez-Lopez N. Amniotic Fluid Cell-Free Transcriptome: A Glimpse Into Fetal Development and Placental Cellular Dynamics During Normal Pregnancy. BMC Med Genomics. 2020 Feb 12;13(1):25. doi: 10.1186/s12920-020-0690-5. PMID: 32050959
  30. Burnham P, Gomez-Lopez N, Heyang M, Cheng AP, Lenz JS, Dadhania DM, Lee JR, Suthanthiran M, Romero R, De Vlaminck I. Separating the Signal From the Noise in Metagenomic Cell-Free DNA Sequencing. Microbiome. 2020 Feb 11;8(1):18. doi: 10.1186/s40168-020-0793-4. PMID: 32046792
  31. Gomez-Lopez N, Romero R, Schwenkel G, Garcia-Flores V, Panaitescu B, Varrey A, Ayoub F, Hassan SS, Phillippe M. Cell-Free Fetal DNA Increases Prior to Labor at Term and in a Subset of Preterm Births. Reprod Sci. 2020 Jan;27(1):218-232. doi: 10.1007/s43032-019-00023-6. Epub 2020 Jan 1. PMID: 32046392
  32. Gomez-Lopez N, Romero R, Hassan SS, Bhatti G, Berry SM, Kusanovic JP, Pacora P, Tarca AL. The Cellular Transcriptome in the Maternal Circulation During Normal Pregnancy: A Longitudinal Study. Front Immunol. 2019 Dec 17;10:2863. doi: 10.3389/fimmu.2019.02863. eCollection 2019. PMID: 31921132
  33. Galaz J, Romero R, Xu Y, Miller D, Slutsky R, Levenson D, Hsu CD, Gomez-Lopez N. Cellular Immune Responses in Amniotic Fluid of Women With Preterm Clinical Chorioamnionitis. Inflamm Res. 2020 Feb;69(2):203-216. doi: 10.1007/s00011-019-01308-x. Epub 2020 Jan 7. PMID: 31912179
  34. Pique-Regi R, Romero R, Tarca AL, Sendler ED, Xu Y, Garcia-Flores V, Leng Y, Luca F, Hassan SS, Gomez-Lopez N. Single cell transcriptional signatures of the human placenta in term and preterm parturition. Elife. 2019 Dec 12;8. pii: e52004. doi: 10.7554/eLife.52004. PubMed PMID: 31829938.
  35. Gomez-Lopez N, Motomura K, Miller D, Garcia-Flores V, Galaz J, Romero R. Inflammasomes: Their Role in Normal and Complicated Pregnancies. J Immunol. 2019  Dec 1;203(11):2757-2769. doi: 10.4049/jimmunol.1900901. Review. PubMed PMID: 31740550; PubMed Central PMCID: PMC6871659.
  36. Gomez-Lopez N, Romero R, Xu Y, Miller D, Arenas-Hernandez M, Garcia-Flores V, Panaitescu B, Galaz J, Hsu CD, Para R, Berry SM. Fetal T Cell Activation in the Amniotic Cavity during Preterm Labor: A Potential Mechanism for a Subset of Idiopathic Preterm Birth. J Immunol. 2019 Oct 1;203(7):1793-1807. doi: 10.4049/jimmunol.1900621. Epub 2019 Sep 6. PubMed PMID: 31492740; PubMed Central  PMCID: PMC6799993.
  37. Hassan SS, Gomez-Lopez N. Reducing maternal mortality: can elabela help in this fight? Lancet. 2019 Jul 6;394(10192):8-9. doi: 10.1016/S0140-6736(19)30543-4. Epub 2019 Jul 4. PubMed PMID: 31282362.
  38. Berkowitz BA, Romero R, Podolsky RH, Lins-Childers KM, Shen Y, Rosales T, Wadghiri YZ, Hoang DM, Arenas-Hernandez M, Garcia-Flores V, Schwenkel G, Panaitescu B, Gomez-Lopez N. QUEST MRI assessment of fetal brain oxidative stress in utero. Neuroimage. 2019 Oct 15;200:601-606. doi: 10.1016/j.neuroimage.2019.05.069. Epub 2019 May 31. PubMed PMID: 31158477; PubMed Central PMCID: PMC6703912.
  39. Slutsky R, Romero R, Xu Y, Galaz J, Miller D, Done B, Tarca AL, Gregor S, Hassan SS, Leng Y, Gomez-Lopez N. Exhausted and Senescent T Cells at the Maternal-Fetal Interface in Preterm and Term Labor. J Immunol Res. 2019 May 23;2019:3128010. doi: 10.1155/2019/3128010. eCollection 2019. PubMed PMID: 31263712; PubMed Central PMCID: PMC6556261.
  40. Arenas-Hernandez M, Romero R, Xu Y, Panaitescu B, Garcia-Flores V, Miller D, Ahn H, Done B, Hassan SS, Hsu CD, Tarca AL, Sanchez-Torres C, Gomez-Lopez N. Effector and Activated T Cells Induce Preterm Labor and Birth That Is Prevented by Treatment with Progesterone. J Immunol. 2019 May 1;202(9):2585-2608. doi: 10.4049/jimmunol.1801350. Epub 2019 Mar 27. PubMed PMID: 30918041; PubMed Central PMCID: PMC6570421.
  41. Leng Y, Romero R, Xu Y, Galaz J, Slutsky R, Arenas-Hernandez M, Garcia-Flores V, Motomura K, Hassan SS, Reboldi A, Gomez-Lopez N. Are B cells altered in the decidua of women with preterm or term labor? Am J Reprod Immunol. 2019 May;81(5):e13102. doi: 10.1111/aji.13102. Epub 2019 Mar 29. PubMed PMID: 30768818; PubMed Central PMCID: PMC6556388.
  42. Gomez-Lopez N, Romero R, Garcia-Flores V, Leng Y, Miller D, Hassan SS, Hsu CD, Panaitescu B. Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes†. Biol Reprod. 2019 May 1;100(5):1306-1318. doi: 10.1093/biolre/ioy264. PubMed PMID: 30596885; PubMed Central PMCID: PMC6497524.
  43. Faro J, Romero R, Schwenkel G, Garcia-Flores V, Arenas-Hernandez M, Leng Y, Xu Y, Miller D, Hassan SS, Gomez-Lopez N. Intra-amniotic inflammation induces preterm birth by activating the NLRP3 inflammasome†. Biol Reprod. 2019 May 1;100(5):1290-1305. doi: 10.1093/biolre/ioy261. PubMed PMID: 30590393; PubMed Central PMCID: PMC6698670.
  44. Miller D, Motomura K, Garcia-Flores V, Romero R, Gomez-Lopez N. Innate Lymphoid Cells in the Maternal and Fetal Compartments. Front Immunol. 2018 Oct 26;9:2396. doi: 10.3389/fimmu.2018.02396. eCollection 2018. Review. PubMed PMID: 30416502; PubMed Central PMCID: PMC6212529.
  45. Garcia-Flores V, Romero R, Miller D, Xu Y, Done B, Veerapaneni C, Leng Y, Arenas-Hernandez M, Khan N, Panaitescu B, Hassan SS, Alvarez-Salas LM, Gomez-Lopez N. Inflammation-Induced Adverse Pregnancy and Neonatal Outcomes Can Be Improved by the Immunomodulatory Peptide Exendin-4. Front Immunol. 2018 Jun 18;9:1291. doi: 10.3389/fimmu.2018.01291. eCollection 2018. PubMed PMID: 29967606; PubMed Central PMCID: PMC6015905.
  46. Frascoli M, Coniglio L, Witt R, Jeanty C, Fleck-Derderian S, Myers DE, Lee TH, Keating S, Busch MP, Norris PJ, Tang Q, Cruz G, Barcellos LF, Gomez-Lopez N,  Romero R, MacKenzie TC. Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-γ and TNF-α. Sci Transl Med. 2018 Apr 25;10(438). pii: eaan2263. doi: 10.1126/scitranslmed.aan2263. PubMed PMID: 29695455; PubMed Central PMCID: PMC6449052.
  47. Gomez-Lopez N, Romero R, Xu Y, Miller D, Leng Y, Panaitescu B, Silva P, Faro J, Alhousseini A, Gill N, Hassan SS, Hsu CD. The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies. Am J Reprod Immunol. 2018 Apr;79(4):e12827. doi: 10.1111/aji.12827. Epub 2018 Mar 3. PubMed PMID: 29500850; PubMed Central PMCID: PMC5951617.
  48. Xu Y, Romero R, Miller D, Silva P, Panaitescu B, Theis KR, Arif A, Hassan SS, Gomez-Lopez N. Innate lymphoid cells at the human maternal-fetal interface in spontaneous preterm labor. Am J Reprod Immunol. 2018 Jun;79(6):e12820. doi: 10.1111/aji.12820. Epub 2018 Feb 19. PubMed PMID: 29457302; PubMed Central PMCID: PMC5948134.
  49. Miller D, Romero R, Unkel R, Xu Y, Vadillo-Ortega F, Hassan SS, Gomez-Lopez N. CD71+ erythroid cells from neonates born to women with preterm labor regulate cytokine and cellular responses. J Leukoc Biol. 2018 Apr;103(4):761-775. doi: 10.1002/JLB.5A0717-291RRR. Epub 2018 Feb 1. PubMed PMID: 29389020; PubMed Central PMCID: PMC5987205.
  50. Gomez-Lopez N, Romero R, Xu Y, Leng Y, Garcia-Flores V, Miller D, Jacques SM, Hassan SS, Faro J, Alsamsam A, Alhousseini A, Gomez-Roberts H, Panaitescu B, Yeo  L, Maymon E. Are amniotic fluid neutrophils in women with intraamniotic infection and/or inflammation of fetal or maternal origin? Am J Obstet Gynecol. 2017 Dec;217(6):693.e1-693.e16. doi: 10.1016/j.ajog.2017.09.013. Epub 2017 Sep 28. PubMed PMID: 28964823; PubMed Central PMCID: PMC5878926.
  51. Gomez-Lopez N, Romero R, Plazyo O, Schwenkel G, Garcia-Flores V, Unkel R, Xu Y, Leng Y, Hassan SS, Panaitescu B, Cha J, Dey SK. Preterm labor in the absence of acute histologic chorioamnionitis is characterized by cellular senescence of the chorioamniotic membranes. Am J Obstet Gynecol. 2017 Nov;217(5):592.e1-592.e17. doi: 10.1016/j.ajog.2017.08.008. Epub 2017 Aug 25. PubMed PMID: 28847437; PubMed Central PMCID: PMC5800423.
  52. Gomez-Lopez N, Romero R, Arenas-Hernandez M, Schwenkel G, St Louis D, Hassan SS, Mial TN. In vivo activation of invariant natural killer T cells induces systemic and local alterations in T-cell subsets prior to preterm birth. Clin Exp Immunol. 2017 Aug;189(2):211-225. doi: 10.1111/cei.12968. Epub 2017 May 10. PubMed PMID: 28369855; PubMed Central PMCID: PMC5508324.
  53. Gomez-Lopez N, Romero R, Xu Y, Garcia-Flores V, Leng Y, Panaitescu B, Miller D, Abrahams VM, Hassan SS. Inflammasome assembly in the chorioamniotic membranes during spontaneous labor at term. Am J Reprod Immunol. 2017 May;77(5). doi: 10.1111/aji.12648. Epub 2017 Feb 24. PubMed PMID: 28233423; PubMed Central PMCID: PMC5429868.
  54. Gomez-Lopez N, Romero R, Leng Y, Garcia-Flores V, Xu Y, Miller D, Hassan SS. Neutrophil extracellular traps in acute chorioamnionitis: A mechanism of host defense. Am J Reprod Immunol. 2017 Mar;77(3). doi: 10.1111/aji.12617. Epub 2017 Jan 3. PubMed PMID: 28045214; PubMed Central PMCID: PMC5370569.
  55. Gomez-Lopez N, Romero R, Xu Y, Miller D, Unkel R, Shaman M, Jacques SM, Panaitescu B, Garcia-Flores V, Hassan SS. Neutrophil Extracellular Traps in the Amniotic Cavity of Women with Intra-Amniotic Infection: A New Mechanism of Host Defense. Reprod Sci. 2017 Aug;24(8):1139-1153. doi: 10.1177/1933719116678690. Epub 2016 Nov 24. PubMed PMID: 27884950; PubMed Central PMCID: PMC6343453.
  56. Plazyo O, Romero R, Unkel R, Balancio A, Mial TN, Xu Y, Dong Z, Hassan SS, Gomez-Lopez N. HMGB1 Induces an Inflammatory Response in the Chorioamniotic Membranes That Is Partially Mediated by the Inflammasome. Biol Reprod. 2016 Dec;95(6):130. doi: 10.1095/biolreprod.116.144139. Epub 2016 Nov 2. PubMed PMID: 27806943; PubMed Central PMCID: PMC5315428.
  57. Furcron AE, Romero R, Mial TN, Balancio A, Panaitescu B, Hassan SS, Sahi A, Nord C, Gomez-Lopez N. Human Chorionic Gonadotropin Has Anti-Inflammatory Effects at the Maternal-Fetal Interface and Prevents Endotoxin-Induced Preterm Birth, but Causes Dystocia and Fetal Compromise in Mice. Biol Reprod. 2016 Jun;94(6):136. doi: 10.1095/biolreprod.116.139345. Epub 2016 May 4. PubMed PMID: 27146032; PubMed Central PMCID: PMC4946806.
  58. Xu Y, Romero R, Miller D, Kadam L, Mial TN, Plazyo O, Garcia-Flores V, Hassan SS, Xu Z, Tarca AL, Drewlo S, Gomez-Lopez N. An M1-like Macrophage Polarization in Decidual Tissue during Spontaneous Preterm Labor That Is Attenuated by Rosiglitazone Treatment. J Immunol. 2016 Mar 15;196(6):2476-2491. doi: 10.4049/jimmunol.1502055. Epub 2016 Feb 17. PubMed PMID: 26889045; PubMed Central PMCID: PMC4779725.
  59. Gomez-Lopez N, Romero R, Plazyo O, Panaitescu B, Furcron AE, Miller D, Roumayah T, Flom E, Hassan SS. Intra-Amniotic Administration of HMGB1 Induces Spontaneous Preterm Labor and Birth. Am J Reprod Immunol. 2016 Jan;75(1):3-7. doi: 10.1111/aji.12443. PubMed PMID: 26781934; PubMed Central PMCID: PMC5029853.
  60. St Louis D, Romero R, Plazyo O, Arenas-Hernandez M, Panaitescu B, Xu Y, Milovic T, Xu Z, Bhatti G, Mi QS, Drewlo S, Tarca AL, Hassan SS, Gomez-Lopez N. Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone. J Immunol. 2016 Feb 1;196(3):1044-59. doi: 10.4049/jimmunol.1501962. Epub 2016 Jan 6. PubMed PMID: 26740111; PubMed Central PMCID: PMC4724534.

 

Patents

Gomez-Lopez Nand Olson DM. "Leukocyte Activation And Methods Of Use Thereof" U.S. International. Publication number WO 2012/097451 A1. Publication date 07/26/2012.